Almost 300 drivers have been caught in the first police operation targeting the whole of the M5.
As well as speeding and mobile phone offences 35 motorists were seen on the 70mph road not wearing a seatbelt.
Officers were called to one report of a man with a handgun on the M5 in Devon.
Seven police forced took part in Operation Unity, which covered 291 motorists, last Thursday and Friday.
70 drivers were stopped for speeding and further 54 have been fined for driving while using a mobile phones.
While forces already share intelligence and respond to incidents across borders, it is the first time officers from CMPG (West Mercia, West Midlands and Staffordshire forces), the newly-formed Tri-force Operations (Avon & Somerset, Gloucestershire and Wiltshire forces) and Devon & Cornwall Police have taken a consistent approach and worked together as one to police the M5.
Superintendent Paul Keasey, head of CMPG who led the operation, said: "We are delighted with the results of this operation, which saw 79 drivers dealt with on the M5 in the West Mercia and West Midlands force areas.
"Recent intelligence indicates the M5 is a vital route for many different members of the criminal community, allowing them to traffic people, convey drugs, transport stolen goods and deliver vehicles following car key burglaries.
"We hope this operation sends a clear message to them that we will act on the information we receive from the public and we will take whatever action necessary to disrupt their activities.
"We also hope it raises the awareness of the 'fatal five' offences, namely dangerous and careless driving, mobile phones, speeding, seatbelts, drink and drug driving, and makes drivers think more carefully about their actions, helping to reduce the number of people killed or seriously injured on our roads."
West Midlands Police and Crime Commissioner, David Jamieson, said: "To keep our motorways safe for everyone and tackle organised crime requires police forces to work together, just as the three-force Central Motorway Police Group has done for many years in our area.
"We know that the motorway network is vital to organised crime, and I am pleased to see forces working together across boundaries to deny its use to criminals. I welcome this operation and hope to see more of its kind in future."
